Recombinant Rat Beta-defensin 4 (Rat BD-4) _ 92272ESDefensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The defensins are distinguished from the defensins by the pairing of their three disulfide bonds. To date, six human defensins have been identified; BD 1, BD 2, BD 3, BD 4, BD 5 and BD 6. defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct

No Exonuclease

The biological activity was determined by its binding ability in a functional ELISA

It can be used for immunoprecipitation (IP) and purification of fusion proteins with HA labels

incubated at 37°C for 4 hours) shows no residual activity

Leu30-Cys226

12:319-336

Ras-Raf-MAPK

also known as cachectin

as well as in adherent and suspension cell cultures

Inhibits Apoptosis

more frequent episodes of hunger

and antagonizes epithelial-mesenchymal transition (EMT)